降脂|剂量翻倍 or 联合治疗?这类病例这样降脂!

这是一例来自基层的血脂异常老年病例 , 基线血脂较高 , 给予了氟伐他汀+依折麦布降脂治疗 , 获得了很好的结果 , 提示目前在基层医院 , 降脂治疗的理念也是与时俱进的 。
【降脂|剂量翻倍 or 联合治疗?这类病例这样降脂!】点评专家
降脂|剂量翻倍 or 联合治疗?这类病例这样降脂!
文章图片


图2患者相关生化指标变化
★专家点评
该病例为高血脂症合并高血压并且高龄患者 , 是基层社区医院常见的患者类型 。提供的材料非常有针对性 , 利于病例的制作 。但是在下诊断时应更加严谨 , “老年高脂血症”应为“高脂血症” , 生化检查提示“甘油三酯3.18 mmol/L , 胆固醇6.86 mmol/L” , 可以考虑在治疗方案中 , 加入贝特类药物进行干预 。
参考文献:
1.Mach F, Baigent C, Catapano AL, et al. 2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk. Eur Heart J, 2020, 41(1): 111-188.
2.HPS2-THRIVE Collaborative Group. HPS2-THRIVE randomized placebo-controlled trial in 25 673 high-risk patients of ER niacin/laropiprant: trial design, pre-specified muscle and liver outcomes, and reasons for stopping study treatment. Eur Heart J, 2013, 34(17):1279-1291.
3.Cannon CP, Blazing MA, Giugliano RP, et al. Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes. N Engl J Med, 2015, 372(25): 2387-2397.
4.Sabatine MS, Giugliano RP, Wiviott SD, et al. Efficacy and safety of evolocumab in reducing lipids and cardiovascular events. N Engl J Med, 2015, 372(16): 1500-1509.
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