长寿|老话说“要想活到老，吃饭七分饱”，真的有科学依据吗？( 三 ) 长寿|细胞

[2] Ma S, Sun S, Geng L, etal. Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape ofRattus Norvegicus Aging. Cell. 2020 Mar 5;180(5):984-1001.e22. doi:10.1016/j.cell.2020.02.008. Epub 2020 Feb 27. PMID: 32109414.
[3] https://new.qq.com/rain/a/20210306A0697G00
[4] Beydoun, S., Choi,H.S., Dela-Cruz, G. et al. An alternative food source for metabolism andlongevity studies in Caenorhabditis elegans. Commun Biol 4, 258 (2021). https://doi.org/10.1038/s42003-021-01764-4
[5] Swindell, W. R. (2012).Dietary restriction in rats and mice: a meta-analysis and review of theevidence for genotype-dependent effects on lifespan. Ageing research reviews,11(2), 254-270.
[6] Adam J. Schindler, L.Ryan Baugh, David R. Sherwood. Identification of Late Larval StageDevelopmental Checkpoints in Caenorhabditis elegans Regulated by Insulin/IGFand Steroid Hormone Signaling Pathways. PLoS Genetics, 2014; 10 (6): e1004426DOI: 10.1371/journal.pgen.1004426
[7] C. Y. Liao, B. A.Rikke, T. E. Johnson, V. Diaz, J. F. Nelson, Genetic variation in the murinelifespan response to dietary restriction: from life extension to lifeshortening. Aging Cell 9, 92-95 (2010).
[8] Mattison, J., Roth, G.,Beasley, T. et al. Impact of caloric restriction on health and survival inrhesus monkeys from the NIA study. Nature 489, 318–321 (2012).https://doi.org/10.1038/nature11432
[9] Colman, R., Beasley,T., Kemnitz, J. et al. Caloric restriction reduces age-related and all-causemortality in rhesus monkeys. Nat Commun 5, 3557 (2014).https://doi.org/10.1038/ncomms4557
[10] Flanagan EW, Most J,Mey JT, Redman LM. Calorie Restriction and Aging in Humans. Annu Rev Nutr. 2020Sep 23;40:105-133. doi: 10.1146/annurev-nutr-122319-034601. Epub 2020 Jun 19.PMID: 32559388.
[11] Belsky DW, Huffman KM,Pieper CF, Shalev I, Kraus WE. Change in the Rate of Biological Aging inResponse to Caloric Restriction: CALERIE Biobank Analysis. J Gerontol A BiolSci Med Sci. 2017 May 22. doi: 10.1093/gerona/glx096.
[12] Wei, M., Brandhorst,S., Shelehchi, M., Mirzaei, H., Cheng, C. W., Budniak, J., ... & Cohen, P.(2017). Fasting-mimicking diet and markers/risk factors for aging, diabetes,cancer, and cardiovascular disease. Science translational medicine, 9(377),eaai8700.
[13] National Institue onAging(NIA). Calorie Restriction and Fasting Diets: What Do We Know?
https://www.nia.nih.gov/health/calorie-restriction-and-fasting-diets-what-do-we-know
[14] http://en.wikipedia.org/wiki/Minnesota_Starvation_Experiment

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【长寿|老话说“要想活到老，吃饭七分饱”，真的有科学依据吗？】
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长寿|老话说“要想活到老，吃饭七分饱”，真的有科学依据吗？( 三 )

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