nsaids|非甾体类抗炎药的前世今生( 二 )
结语
从1899年NSAIDs原形药物阿司匹林的问世开始,我们见证了NSAIDs药物百年曲折的成长道路 。从有严重不良反应的保泰松,到不良反应相对减少的布洛芬、双氯芬酸钠,再到胃肠道风险显著降低但心血管风险增高的罗非昔布,直至如今胃肠道风险低且不增加心血管风险的特异性COX-2抑制剂塞来昔布,学者对NSAIDs的探索之路从未止步 。
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